Moreover, IL-35 expression was negatively correlated with NKp46 expression (Spearman r = –0.526, P = 0.000) (Figure 2F), and the NKp46/CD45 ratio exhibited a statistically significant difference between the EGFR-mutant and EGFR-wild-type NSCLC groups (t=-9.083,P=0.000)(Figure 2G). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.