Conversely, ELFN1 was significantly downregulated in 13 tumor types, including adrenocortical carcinoma (ACC), breast carcinoma (BRCA), cervical squamous cell carcinoma (CESC), cholangiocarcinoma (CHOL), kidney chromophobe (KICH), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), pan-kidney cohort (KIPAN), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD), prostate adenocarcinoma (PRAD), uterine corpus endometrial carcinoma (UCEC), and Wilms tumor (WT). This evidence concerns the gene ELFN1 and cholangiocarcinoma.