Given the high expression of ELFN1 in CRC cells, we transfected CRC cell lines HCT8 and Caco-2 with sh-NC (negative control) and sh-ELFN1 (ELFN1 knockdown) (Figure 11C) and evaluated their effects on cell proliferation, motility, and migration. This evidence concerns the gene ELFN1 and colorectal carcinoma.