CRP and lymphopenia: As far as laboratory parameters is concerned, cluster 1 included flares characterized by marked CRP elevation (6.4 ± 8 vs 2.9 ± 6.6 and 0.8 ± 1.1 mg/dL, p=0.000), a trend for higher ferritin serum levels and lymphopenia (901.2 ± 590.4 vs 1254.2 ± 559.3 and 1219.7 ± 635.5 Ux109/L, p=0.000) compared to the other clusters.