As shown in Table 4, univariate Cox regression analysis revealed that patients with PN/REE > 0.6 (HR 2.755, 95% CI 1.665–4.558, p < 0.001), daily PN fluid volume > 1,650 mL (HR 1.862, 95% CI 1.138–3.047, p = 0.013), neutrophils < 1.5 × 109/L (HR 3.140, 95% CI 1.843–5.348, p < 0.001), LYC < 1 × 109/L (HR 1.934, 95% CI 1.007–3.716, p = 0.048), anemia (HR 1.745, 95% CI 1.009–3.020, p = 0.046), and albumin < 35 g/L (HR 1.886, 95% CI 1.145–3.106, p = 0.013) had significantly increased risk of developing CRBSI. The gene discussed is ALB; the disease is anemia.