EGFR and keratosis pilaris: Notably, immune-related pathways, including immunoregulatory interactions, neutrophil degranulation, innate immune system activation, and chemokine receptor-ligand interactions, were also enriched in KP tumors, suggesting a more active immune microenvironment in KRAS-mutant LUAD compared to the immunosuppressive TME observed in EGFR-mutant LUAD.