USP32, USP1, USP37, USP12, and USP6 are elevated in macrophages (Figure 2E), while USP32, USP9X, USP46, USP12, USP36, and USP24 are upregulated in classical monocytes of colon cancer relative to the control group (Figure 2G). The gene discussed is USP46; the disease is colonic neoplasm.