The results showed a significant reduction in cell viability (Figure 6E), proliferation (Figure 6F), invasion (Figure 6G-H), colony formation (Figure 6I-J) and migration (Figure 6K-L) in USP32-KO HCT116 and SW480 cells when compared with mock controls, suggesting that the loss of USP32 inhibits CRC growth. Here, USP32 is linked to colorectal carcinoma.