Ni et al. reported that miR-106b is capable of inhibiting proliferation and immigration by suppressing MMP-2 which leads to the inactivation of extracellular signal-regulated kinases (ERK) and increases the activity of osteoblasts via MiR106b/MMP-2/ERK pathway that can lead to BC bone metastasis [72] (Table 2). This evidence concerns the gene MMP2 and breast cancer.