After correcting for age, pre-pregnancy BMI, gestational age at sampling, and fasting insulin and glucose levels, GDM subjects with the H2 allele (H1H2 + H2H2) at the -317H1/H2 polymorphism showed decreased TC, LDL-C, apoB, and AI compared to those with the H1H1 genotype (P < 0.05–0.001, Table 4, Figures 1A-D). This evidence concerns the gene INS and gestational diabetes.