In the coinfection group, the lymphocyte (lym) count decreased significantly (0.47 vs. 0.60×109/L, P < 0.001), prothrombin time (PT), activated partial thromboplastin time (APTT), and thrombin time (TT) were all significantly prolonged (P < 0.001);Additionally, patients in the coinfection group generally presented with hypocalcemia (1.89 vs. 1.94 mmol/L), elevated renal function indicators (Urea. The gene discussed is F2; the disease is serum urea amount.