Currently approved ASO‐based treatments include eplontersen for hereditary transthyretin amyloidosis with polyneuropathy,28 olezarsen for familial chylomicronemia syndrome,29 eteplirsen for Duchenne muscular dystrophy30 and tofersen for superoxide dismutase 1 (SOD1) related ALS.31 The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.