RBFOX3 and Cognitive impairment: This has been observed in the DH model, where hippocampal LTP is normal at 1 week after stroke, then progressively worsens up to 12 weeks after stroke, and is associated with a cognitive deficit.22 However, there was no relationship between the presence of hippocampal neuronal injury or changes in thalamic NeuN density and NOR performance in this study.