Among the population of CD68+ cells, CD206+CD68+ (M2) and CD86+CD68+ (M1) cells accounted for 36.2% and 12.7%, respectively, of the population in tumor-surrounding tissues, whereas they accounted for 13.2% (M2) and 45.3% (M1) of the population in normal tissues (Fig. 1A). The gene discussed is CD86; the disease is neoplasm.