Moreover, among all BMDM subgroups, tumor size in the siNSUN2 group is smallest, and tumor size in the siNSUN2-siSOCS3 group and the NC group don’t have a significant difference, indicating that knock-down of NSUN2 inhibited tumor growth in vivo while SOCS3 rescued this inhibition (Fig. 6C, D). This evidence concerns the gene NSUN2 and neoplasm.