Importantly, compared to castration-sensitive prostate cancer (CSPC) tissues, CRPC tissues exhibited significantly higher mRNA levels of SNRPA, NDUFS8, and NDUFS9 (Fig. 8O–Q), as well as increased ATP contents (Fig. 8R) and mtDNA levels (Fig. 8S). This evidence concerns the gene SNRPA and Familial prostate cancer.