To evaluate whether EP300Mut cells are sensitive to PARPi, Rev1i and POLQi, we exposed EP300Mut/WT NA-ATLL cells to these inhibitors and assessed apoptotic fractions in the cells by flow cytometry, co-staining for Annexin V (apoptotic marker) and PI. The gene discussed is ANXA5; the disease is adult T-cell leukemia/lymphoma.