TP53 and cancer: Concurrently, pathway analyses revealed significant alterations in p53 signalling and oxidative phosphorylation, suggesting that PLA2R1 suppression might facilitate tumour cell survival through diminished ROS‐induced apoptosis and senescence that mechanisms have been previously established in other cancers [57, 58, 60, 68], Similarly, our data provide concrete evidence for PFN2 regulation through identified ceRNA axes, including hsa‐miR‐4732‐5p sponged by AC016705 and STEAP3‐AS1, and hsa‐miR‐372‐3p sponged by STEAP3‐AS1.