In addition, we also found faint positive signals for the plasma membrane proteins Caveolin‐3 and DHPR, accrediting previous studies reporting the presence of DHPR in tubular aggregates in patients with congenital myasthenic syndrome (CMS) [20] and indicating that tubular aggregates are not solely composed of SR proteins. The gene discussed is RNPS1; the disease is Congenital myasthenic syndromes.