Carboplatin‐resistant ovarian cancer models reveal that HMGB1 boosts NER and HRR by recruiting repair factors such as XPA and RAD51—siRNA‐mediated HMGB1 silencing induces accumulated DNA damage, elevates apoptosis, and reduces carboplatin IC50 by nearly an order of magnitude [119, 120]. This evidence concerns the gene HMGB1 and ovarian carcinoma.