In the differential analyses between normal and tumor tissues, we examined the updated glioma classification, encompassing all gliomas, IDH‐wildtype astrocytomas (IDHwt), IDH‐mutant astrocytomas (IDHmu), and oligodendrogliomas (Oligo), to assess the mRNA expression levels of TMEM106A, TMEM106B, and TMEM106C. Here, TMEM106C is linked to astrocytoma (excluding glioblastoma).