To further elucidate the functional impact of TMEM106A overexpression in gliomas, we performed gene set enrichment analysis (GSEA) across three principal molecular subtypes: IDH‐wildtype astrocytomas (IDHwt), IDH‐mutant astrocytomas (IDHmu), and oligodendrogliomas (Oligo). This evidence concerns the gene TMEM106A and astrocytoma (excluding glioblastoma).