To further elucidate the functional impact of TMEM106A overexpression in gliomas, we performed gene set enrichment analysis (GSEA) across three principal molecular subtypes: IDH‐wildtype astrocytomas (IDHwt), IDH‐mutant astrocytomas (IDHmu), and oligodendrogliomas (Oligo). The gene discussed is IDH1; the disease is central nervous system cancer.