The correlation of ERBB2 with PI3K-driven signaling pathways in FTC, observed through GSVA scores and expression correlations with AKT2 and RPS6KB2, aligns with previous findings in canine FTC17; protein expression of ERBB2 (HER2) aligned with gene expression and distribution was also similar to a recent retrospective canine FTC study57. The gene discussed is PIK3CA; the disease is thyroid cancer, nonmedullary, 2.