In monocyte-derived dendritic cells (moDCs) from ITP patients, the mTORC1 signaling pathway is markedly upregulated, resulting in the synthesis of co-stimulatory markers CD80/CD86 and pro-inflammatory cytokines IL-6 and IL-12, thus exacerbating systemic inflammation [60–62]. This evidence concerns the gene CD86 and autoimmune thrombocytopenic purpura.