Peroxisome proliferator-activated receptor γ (PPARγ) is the key transcriptional regulator of adipogenesis and directly triggers many genes involved in adipocyte lipid storage [35], including perilipin 1 (PLIN1) [36]. Since the expression of this transcriptional factor was decreased upon exposure of adipocytes to CRC cells (Fig. 5D), we investigated the expression level of other proteins involved in lipid uptake and storage in adipocytes. Here, PLIN1 is linked to colorectal carcinoma.