Urinary NGAL and IL-18 distinguished ATN from other causes of AKI with AUROCs of 0.878 and 0.885 which is comparable to the values obtained by Belcher et al. and the meta-analysis by Puthumana et al. NGAL values in our cohort of HRS and pre-renal AKI patients were similar, unlike those previous studies, which is attributable to our small sample size [19, 20]. This evidence concerns the gene IL18 and acute kidney injury.