CCL2 and hepatocellular carcinoma: The components of the CCL family that are generally increased in senescent cells include MCP-1, 2, and −4 (CCL-2, −8, and −13); HCC-4 (CCL-16); eotaxin-3 (CCL-26); and macrophage inflammatory protein (MIP)−3α and −1α (CCL-3, −20) [24].