PRL and neoplasm: The binary logistic regression, which included the variables of age at surgery, sex, preoperative tumour volume, Knosp grade ≥ 3, preoperative prolactin levels and SCT (n = 77, SGT 62 and SCT 15), revealed that harbouring a SCT, compared with harbouring a SGT, was associated with a significantly increased likelihood of having postoperative pituitary failure (OR 6.4 (CI: 1.20–34.42), p = 0.03).