We found that high NKAIN1 expression was associated with moderate HER2 expression (χ2 = 9.636, P = 0.008), deeper tumor invasion (χ2 = 9.438, P = 0.024), moderate to extensive lymph node metastases (χ2 = 8.632, P = 0.035), and advanced TNM stage (χ2 = 8.753, P = 0.013) (Table 1). This evidence concerns the gene NKAIN1 and neoplasm.