It would be therefore prudent or even necessary to investigate the mother of a newborn with refractory hypoglycaemia and (b) the lack of concordance between the kinetics and dynamics of kon and koff of IAA affecting maternal and newborn dysglycaemia in vivo and the measurement of insulin by immunoassays, which use high-affinity capture antibody quickly followed by quantitation with no/minimum dissociation from capture antibodies. Here, INS is linked to Hypoglycemia.