We showed the top 10 significant terms, and the PLS1- genes were mainly enriched in the GO biological processes (BP), such as “presynapse”, “substantia nigra development”, “synaptic signaling”, “developmental maturation”, “regulation of metal ion transport”, and significantly enriched in one KEGG pathway, which was “Parkinson’s disease” (p < 0.05, Fig. 5A). Here, PLS1 is linked to Parkinson disease.