The expression pattern of TGFβ-1, IL19, CXCR4, BMP1, VCAN, and WNT2 in different molecular subclasses of Breast Cancer revealed that TGFβ-1, IL19, CXCR4, BMP1, VCAN, and WNT2 mRNA levels are higher in luminal A followed by luminal B, HER2 and Basal like respectively (Fig 8). This evidence concerns the gene VCAN and breast cancer.