MKI67 and neoplasm: To further demonstrate the effectiveness of Mito-NPs with 808-nm light irradiation, tumor biopsy including hematoxylin and eosin (H&E) staining, immunohistochemical staining with the nuclear-associatedantigenki-67 (ki67) marker (proliferating cell marker), and terminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick end labeling (TUNEL) assay, was applied.