Further comparison analysis revealed that deregulation of FER1L4, DBH, and NRG1 was consistently observed across liver tissue and PBMCs in patients with chronic viral hepatitis infections (HBV, HCV, and HDV), suggesting that the observed disturbances are not purely tumor‐intrinsic but may reflect systemic immune and metabolic stress associated with chronic infection (Figure 7d). This evidence concerns the gene DBH and neoplasm.