In a myc-induced obesity-driven mouse model of prostate cancer, immunofluorescence staining of ventral prostate tissue shows high levels of CXCL12 in stromal compartments and high staining of CXCR4 and CXCR7 in tumor epithelial compartments (Saha et al., 2017). This evidence concerns the gene CXCL12 and Familial prostate cancer.