We focused on dopaminergic neurons in PD given the connection between Nocturnin, NADPH metabolism, and PD pathology in the literature (Charbonnier-Beaupel et al., 2015; Heiman et al., 2014; Simunovic et al., 2008; Yang et al., 2025; Yang et al., 2008; Zhou et al., 2018). The gene discussed is NOCT; the disease is Parkinson disease.