PSAD was markedly elevated in patients with PCa (0.235 ± 0.024 ng/mL/cm3) compared to patients with BPH (0.067 ± 0.010; p < 0.0001), while PSA-AV was significantly lower in patients with PCa (379.99 ± 51.29) than in patients with BPH (2756.19 ± 791.97; p = 0.0267). The gene discussed is KLK3; the disease is posterior cortical atrophy.