- Inhibited development of experimental autoimmune encephalomyelitis (EAE)- Reduced leukocyte infiltration into CNS- Increased Treg cells and anti-inflammatory cytokines (IL-10, TGF-β)- Decreased Th17 cells and pro-inflammatory cytokines (IL-17, IL-6). This evidence concerns the gene IL10 and experimental autoimmune encephalomyelitis.