- Improved anxiety and depressive-like behaviors- Reduced proinflammatory cytokines (TNF-α, IFN-γ, IL-1β, IL-2, IL-6)- Increased neurotrophic factors (NT-3, BDNF, NGF)- Increased striatal dopamine and metabolite levels- Protection of dopaminergic neurons in substantia nigra. Here, IL1B is linked to Anxiety.