FHIT was identified as a protective factor for pancreatic cancer via Mendelian randomization, showing a significant negative correlation with CHST11 in TCGA (R = -0.23) and lower expression in naïve T cell_ CHST11pos than in naïve T cell_ CHST11neg (Figures 8I–J, L). This evidence concerns the gene FHIT and familial pancreatic carcinoma.