Bioactive compounds such as flavonoids, triterpenoids, steroids, tannins, phytosterols, and saponins have been shown to modulate oxidative stress markers (↑SOD, CAT, GSH; ↓MDA, nitrite), reduce aberrant crypt foci (ACF) counts, and histological restoration in colon cancer thereby demonstrating anti-tumor, chemopreventive and antioxidant properties (150). This evidence concerns the gene CAT and colonic neoplasm.