STAT3 and ovarian carcinoma: Asiatic acid enhances mitochondrial damage, modulates YAP1, VEGFA, STAT3, and inhibits EMT (86, 87), while also suppressing PI3K/Akt/mTOR signaling to promote autophagy and apoptosis in lung, colon, and ovarian cancers [88–94].Phytochemicals such as alkaloids, glycosides, and flavonoids induce mitochondrial dysfunction, oxidative stress, and caspase-mediated apoptosis in MCF-7, A549, HeLa, and Caco-2 cells (95).