1. Activates the STAT3/MAPK pathway, promotes the proliferation of tumor cells, and inhibits apoptosis;2. Induces the EMT process and enhances the metastatic potential of tumor cells;3. Promotes hepatic glycogenolysis to provide energy for tumor cells;4. Accelerates the proliferation of vascular endothelial cells and promotes tumor angiogenesis. This evidence concerns the gene STAT3 and neoplasm.