1. Activates the STAT4 pathway, promotes the differentiation of Th1 cells, and enhances cellular immune responses;2. Enhances the cytotoxicity of CD8+ CTLs and NK cells, and promotes the secretion of IFN-γ;3. Intratumoral injection or gene therapy: Remodels the TME and inhibits tumor growth. This evidence concerns the gene IFNG and neoplasm.