Pathway enrichment analysis showed that these DEGs were enriched in key pathways involved in sepsis, including “Th1 and Th2 cell differentiation”, “T cell receptor signaling pathway”, and “PD-L1 checkpoint pathway in cancer”, as well as cell death-related pathways such as “Apoptosis”, “Cellular Senescence”, and the “p53 Signaling Pathway”. This evidence concerns the gene CD274 and cancer.