EOMES and myeloid sarcoma: Indeed, a high level of perivascular inflammation, characterized by T and B cells, and active demyelination are associated with rapid progression in a post-mortem study.38 This is in line with findings from our group demonstrating that patients with pregnancy in MS showed a correlation of Eomes+ Th cells with reduced Treg cells and a significant increase of B-cells during the third trimester and a positive correlation with disability post-partum.14