CTLA4 and bladder transitional cell carcinoma: Surprisingly, we found that high expression of the top three genes with risk coefficients greater than 0 (ADCY7, SLC1A6, NELL2) was detrimental to the survival prognosis of BLCA patients (Figures 6A–C), while high expression of the three genes with the smallest risk coefficients less than 0 (ITGB7, ZNF823, CTLA4) was beneficial for their survival prognosis (Figures 6D–F).