SOD1 and Cognitive impairment: In conclusion, the findings of the present study highlights the neuroprotective potential of decanoic acid, on cognitive impairment, and neurotoxicity associated with D-gal and D-gal/AlCl3 treated mice possibly through modulation of aging hallmarks, specifically, by enhancing antioxidant activity (GSH, SOD, CAT), promoting autophagy by regulating nutrient sensing pathways, primarily inhibiting mTOR expression and improving enzymatic levels of p-AMPK, and reducing the frequency of senescence-associated β-galactosidase positive neuronal cells.