Huda et al. 48 have shown that dysregulation of inflammatory pathways occurs predominantly in the visceral adipose tissue, with activation of macrophages and increased TNF-α and IL-6 expressions in that tissue, but not in the subcutaneous fat, emphasizing that, in preeclampsia, dysregulation of inflammatory pathways occurs predominantly in the visceral adipose tissue. Here, TNF is linked to preeclampsia.