MYC and psoriasis: Elevated MYC signaling is also implicated in psoriasis (Elder et al., 1990; Leng et al., 2024), and skin expressing psoriasis-associated GoF CARD14 mutants have both elevated MYC signatures and psoriatic features (e.g., epidermal hyperproliferation, parakeratosis) (DeVore et al., 2024).