In MCI group, diabetes prevalence, hyperuricemia prevalence, arteriosclerosis prevalence, education level, MMSE score, MoCA score, AD8 score and HbA1c were higher, while weight, BMI, SUA, TC, LDL, Alb, TT3, TSH, and FT3 were lower (p < 0.05). This evidence concerns the gene ALB and diabetes mellitus.