GFAP and dementia: We found an increase in both GFAP labeling intensity (IntDen) and area covered (%) in the CA3 region of the hippocampus of OVX mice regardless of dementia type [Fig. 4C, main effect of OVX p = 0.0252, F (1, 21) = 5.805, and Fig. 4D p = 0.0324, F (1, 21) = 5.248, respectively].