VEGFA and colorectal carcinoma: VEGF levels revealed dramatic differences between groups, with markedly higher concentrations in the CRC group (260.8 ± 14.6 pg/mL) compared to the benign (180.1 ± 11.4 pg/mL) and control groups (40.7 ± 2.6 pg/mL), with statistical significance (p = 0.018) (Table 2).