Of the 109 proteins found to be associated with infection, 5 in T cell-derived EVs (PSME1, MTREX, H2B1C, FBLN1 and DYL2), 2 in B cell-derived EVs (SDHA and COHA1) and 4 in monocyte-derived EVs (DPP3, PCSK9, HCD2 and CMC1) showed differential abundance according to outcome. The gene discussed is PSME1; the disease is infection.