To confirm the involvement of N-cadherin in the regulation of OSA cell migration, we transfected SAOS-LM5 wt cells with siRNA against CDH2. Subsequent scratch assay analysis revealed slower migration of CDH2 knock-down cells compared to cells transfected with negative control siRNA (Fig. 5b, c; Supplementary Fig. 4e). Here, CDH2 is linked to obstructive sleep apnea syndrome.