Next, to further test the hypothesis of possible epigenetic activity in the chromosome 1p36 region or in GNB1, we analysed whole-genome bisulfite-seq methylation data in four different cancer types, including for (a) paediatric brain cancer (PBCA-DE) and (b) soft tissue cancer - Ewing sarcoma (BOCA-FR) (see methods). The gene discussed is GNB1; the disease is Ewing sarcoma.