FASN and cancer: For instance, Fiorentino et al. found that the fatty acid synthase (FASN), a cornerstone of protein palmitoylation, is overexpressed in prostate cancer and is associated with the palmitoylation of Wnt1 and the cytoplasmic stabilization of β-catenin, processes that may promote anti-apoptotic capabilities and proliferation in cancer cells [21,22].